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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2073808Generated: October 31, 2026

HCID 14499846, compound → HCID 14499848, compound

https://huagongshe.com/reaction/2073808

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 14499846HCID 14499846—
SolventMethanolHCID 887—
SolventWaterHCID 962—
SolventSodium CarbonateHCID 10340—
ProductHCID 14499848HCID 1449984898.1%

Reaction Steps

8-[2Methyl-6-(2-acetoxyacetyl)aminobenzylamino]3-(2-propynyl)-2 -methylimidazo[1,2-a]pyridine (0.33 g) was dissolved in a mixture of an aqueous solution (0.7 ml) of sodium carbonate (0.0118 g) and methanol (6.6 ml) at room temperature and then the mixture was stirred for 4 hours. The mixture was diluted with water and the resultant solid was collected to give 8-[2-methyl- 6-(2-hydroxyacetyl)aminobenzylamino]-3-(2-propynyl)-2-methylimidazo[1,2-a]pyridine (0.29 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04920129
Source datasetuspto-grants-1990_04
ORD IDord-524da66d424c4a6a99c1fc091896da76
Source noteuspto-grants-1990_04