HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 14499846, compound → HCID 14499848, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 14499846 | HCID 14499846 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | Sodium Carbonate | HCID 10340 | — |
| Product | HCID 14499848 | HCID 14499848 | 98.1% |
Reaction Steps
8-[2Methyl-6-(2-acetoxyacetyl)aminobenzylamino]3-(2-propynyl)-2 -methylimidazo[1,2-a]pyridine (0.33 g) was dissolved in a mixture of an aqueous solution (0.7 ml) of sodium carbonate (0.0118 g) and methanol (6.6 ml) at room temperature and then the mixture was stirred for 4 hours. The mixture was diluted with water and the resultant solid was collected to give 8-[2-methyl- 6-(2-hydroxyacetyl)aminobenzylamino]-3-(2-propynyl)-2-methylimidazo[1,2-a]pyridine (0.29 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04920129 |
| Source dataset | uspto-grants-1990_04 |
| ORD ID | ord-524da66d424c4a6a99c1fc091896da76 |
| Source note | uspto-grants-1990_04 |