反应详情

To a solution of 8-(2-methyl-6-methoxycarbonylaminobenzylamino)-3-(2-propynyl)-2-methylimidazo[1,2-a]pyridine (0.5 g) in methanol (23 ml) was added dropwise 20%-ethanolic hydrogen chloride (0.5 ml) at 5°-10° C. and the mixture was stirred for 1 hour. A solid was collected to give 8-(2-methyl-6-methoxycarbonylaminobenzylamino)-3-(2-propynyl)-2-methylimidazo[1,2-a]pyridine hydrochloride (0.27 g).

1. customA solid was collected