Dichloromethane → HCID 14800669, compound

HRID 2073874Notes

Reaction equation

HRID 2073874 reaction equation
[N:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][C:2]=1[CH2:11][O:12][C:13]1[CH:28]=[CH:27][C:16]([CH2:17][C:18]2[CH:19]=[C:20]([CH:24]=[CH:25][CH:26]=2)[C:21](O)=[O:22])=[CH:15][CH:14]=1.[Cl:29]CCl>CN(C)C=O>[N:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][C:2]=1[CH2:11][O:12][C:13]1[CH:28]=[CH:27][C:16]([CH2:17][C:18]2[CH:19]=[C:20]([CH:24]=[CH:25][CH:26]=2)[C:21]([Cl:29])=[O:22])=[CH:15][CH:14]=1

Participants

4

Reactant 2

HCID 6344DichloromethaneHCID 14800668HCID 14800668, compound

Product 1

HCID 14800669HCID 14800669, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideCatalyst

Procedure

To (0.05 mol) of 3-(4-(2-quinolinylmethyloxy)benzyl)benzoic acid in dichloromethane solution (500 mol) and chilled in an ice bath is added thionyl chliride (0.06 mol) and a few drops of dimethylformamide. Upon completion of the reaction, the clear solution is evaporated to give 3-(4-(2-quinolinylmethyloxy)benzyl)benzoyl chloride.

Workup

  1. customUpon completion of the reaction
  2. customthe clear solution is evaporated

Sources & evidence

ORD record
ord-a319f2a25364455aaffa6e5fdb44d071
Source dataset
uspto-grants-1990_04
Patent number
US04920133

Reaction notes

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