反应详情

At room temperature, a solution of 3.09 g (0.0127 mol) of ethyl 2-amino-4-bromobenzoate and 30 ml absolute ethanol was saturated with dry hydrogen chloride gas. A colorless precipitate formed in the warm solution. When it was again at room temperature, the solution was diluted with 30 ml of diethyl ether; the resulting crystalline product was filtered and washed with diethyl ether. Thus there was obtained 2.72 g (77%) of the title compound: m.p. 147°-150° C.

1. customAt room temperature
2. customA colorless precipitate formed in the warm solution
3. customwas again at room temperature
4. filtrationthe resulting crystalline product was filtered
5. washwashed with diethyl ether