HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Acid → 4-(4-(2-Quinolinylmethylsulfonyl)phenoxymethyl)benzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Acid | HCID 176 | — |
| Reactant | Hydrogen Peroxide | HCID 784 | — |
| Reactant | 4-(4-(2-Quinolinylmethylsulfinyl)phenoxymethyl)benzoic acid | HCID 14774161 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 4-(4-(2-Quinolinylmethylsulfonyl)phenoxymethyl)benzoic acid | HCID 14774162 | — |
Reaction Steps
To 3 mmol of the sulfinyl compound from Step A in acetic acid (40 mmol) is added 30% hydrogen peroxide (2 ml). The mixture is stirred at ambient temperature and assayed by TLC. Upon disappearance of the sulfinyl starting compound, the reaction mixture is diluted with dichloromethane, washed with dilute aqueous sodium bisulfite and water, dried and evaporated to give 4-(4-(2-quinolinylmethylsulfonyl)phenoxymethyl)benzoic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04920132 |
| Source dataset | uspto-grants-1990_04 |
| ORD ID | ord-b8209a13935c469db8acc87caeabd7c6 |
| Source note | uspto-grants-1990_04 |