反应详情

0.50 g (2.5 mmol) of ethyl 1-methyl-4-nitro-1H-imidazole-2-carboxylate are dissolved in 7.5 ml of ethanol, 0.13 g (0.13 mmol) of palladium-on-carbon (10%) are added and the mixture is hydrogenated at 3 bar for 12 h. The reaction solution is then filtered through kieselguhr and the filtrate is concentrated. The residue is dried in vacuo and reacted further without further purification.

1. filtrationThe reaction solution is then filtered through kieselguhr
2. concentrationthe filtrate is concentrated
3. customThe residue is dried in vacuo
4. customreacted further without further purification