Trifluoroacetic acid → HCID 178525854, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of tert-butyl [5-(4-fluorobenzyl)-3-(1-trityl-1H-imidazol-4-yl)-1H-pyrazol-1-yl]acetate (0.5 g, 0.80 mmol) in CH2Cl2 (10 mL) was added dropwise TFA (10 mL) at 0° C. After the addition, the mixture was stirred at 0° C. for 2 hours. The solvent was removed in vacuo and the residue was washed with Et2O (3×10 mL) and dried in oven to yield the title compound (0.2 g, 80.0%) as a white solid.

Provenance & Evidence