HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-Butyl (2S)-2-(aminomethyl)piperidine-1-carboxylate → (S)-2-(1,8-Naphthyridin-2-ylamino)methyl-piperidine-1-carboxylic acid tert butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-Butyl (2S)-2-(aminomethyl)piperidine-1-carboxylate | HCID 1502020 | — |
| Reactant | 2-Chloro-1,8-naphthyridine | HCID 5152838 | — |
| Product | (S)-2-(1,8-Naphthyridin-2-ylamino)methyl-piperidine-1-carboxylic acid tert butyl ester | HCID 86626012 | 70.8% |
Reaction Steps
The title compound (0.28 g) was prepared from (S)-2-aminomethyl-piperidine-1-carboxylic acid tert-butyl ester (0.35 g) and 2-chloro-1,8-naphthyridine (0.19 g) according to the method of D30.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07919507B2 |
| Source dataset | uspto-grants-2011_04 |
| ORD ID | ord-10f5563437d9460a99c65ae2ce8b3810 |
| Source note | uspto-grants-2011_04 |