Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2074394Generated: October 26, 2026

tert-Butyl (2S)-2-(aminomethyl)pyrrolidine-1-carboxylate → (S)-2-[(6,7-Difluoro-quinoxalin-2-ylamino)-methyl]-pyrrolidine-1-carboxylic acid tert butyl ester

https://huagongshe.com/reaction/2074394

Reaction equation

Participants

RoleNameHCIDCharge
Reactanttert-Butyl (2S)-2-(aminomethyl)pyrrolidine-1-carboxylateHCID 1512533—
Reactant2-Chloro-6,7-difluoroquinoxalineHCID 10375543—
Product(S)-2-[(6,7-Difluoro-quinoxalin-2-ylamino)-methyl]-pyrrolidine-1-carboxylic acid tert butyl esterHCID 8662601358.3%

Reaction Steps

The title compound (0.53 g) was prepared from (S)-2-aminomethyl-pyrrolidine-1-carboxylic acid tert-butyl ester (0.5 g) and 2-chloro-6,7-difluoroquinoxaline (0.5 g) according to the method of D30.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07919507B2
Source datasetuspto-grants-2011_04
ORD IDord-6b8390644f6a42b29affb89328749a83
Source noteuspto-grants-2011_04