Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Propylamine | HCID 7852 | — |
| Reactant | Methyl 3-{[(1-ethoxyethylidene)amino]oxy}propanoate | HCID 71331645 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 57869854 | HCID 57869854 | 86% |
Reaction Steps
To a known compound, 3-(1-ethoxy-ethylideneaminooxy)-propanoic acid methyl ester (CAS No. 97164-30-2, 300 mg, 1.585 mmol) were added methanol (3 ml) and n-propylamine (1.3 ml), and the mixture was stirred at 55° C. for 15 hours. The reaction mixture was concentrated under reduced pressure, and the residue was purified by silica gel column chromatography to give N-(2-propylcarbamoyl-ethoxy)-acetimidic acid ethyl ester (296 mg, 86% yield).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07745663B2 |
|---|
| Source dataset | uspto-grants-2010_06 |
|---|
| ORD ID | ord-cdbdab0d045348dd836917e4c0d1343b |
|---|
| Source note | uspto-grants-2010_06 |
|---|
