Ethanol → HCID 86600963, compound

HRID 2074982Notes

Reaction equation

HRID 2074982 reaction equation
C(OC([NH:11][NH:12][C:13](=[O:32])[C@@H:14]([CH2:20][NH:21][C:22](OCC1C=CC=CC=1)=[O:23])[CH2:15][CH2:16][CH2:17][CH2:18][CH3:19])=O)C1C=CC=CC=1.CC[OH:35]>[Pd]>[NH:12]([C:13]([C@H:14]([CH2:15][CH2:16][CH2:17][CH2:18][CH3:19])[CH2:20][N:21]([OH:35])[CH:22]=[O:23])=[O:32])[NH2:11]

Participants

4

Reactant 2

HCID 702EthanolHCID 67089774HCID 67089774, compound

Product 1

HCID 86600963HCID 86600963, compound

Reagents, catalysts & solvents 1

HCID 23938PalladiumCatalyst

Procedure

To a solution of N′-{(R)-2-[(Benzyloxyformylamino)methyl]heptanoyl]-hydrazinecarboxylic acid benzyl ester (1 mmol) in EtOH (10 mL) was added 10% Pd/C (50 mg). The mixture was subjected to hydrogenation for 5 hours at room temperature and then filtered through Celite. The filtrate was evaporated and purified by hplc to afford N-[(R)-2-(Hydrazinocarbonyl)-heptyl]-N-hydroxy-formamide as a glass. MH+218.

Workup

  1. filtrationfiltered through Celite
  2. customThe filtrate was evaporated
  3. custompurified by hplc

Sources & evidence

ORD record
ord-dbb3c125381d4ce7bf477bb2d16713f5
Source dataset
uspto-grants-2011_04
Patent number
US07919528B2

Reaction notes

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