HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl iodide → HCID 58968720, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | Benzonitrile, 4-(trifluoromethyl)- | HCID 67995 | — |
| Reactant | HCID 58968691 | HCID 58968691 | — |
| Reactant | HCID 178418443 | HCID 178418443 | — |
| Reactant | HCID 178419651 | HCID 178419651 | — |
| Product | HCID 58968720 | HCID 58968720 | — |
Reaction Steps
This compound was prepared by an analogous series of reactions to that used for the preparation of N-(2-(1-cyclopentyl-2-methoxypropan-2-yl)-5-(trifluoromethyl)benzyl)-N-(3,5-bis(trifluoromethyl)benzyl)-2-methyl-2H-tetrazol-5-amine from 2-((3,5-bis(trifluoromethyl)benzyl)(2-methyl-2H-tetrazole-5-yl)amino)methyl)-4-(trifluoromethyl)benzonitrile by the addition of cyclohexylmagnesium bromide followed by ethylmagnesium bromide then alkylation with methyl iodide. LC-MS calc 637.5, found 638.5 (M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07919506B2 |
| Source dataset | uspto-grants-2011_04 |
| ORD ID | ord-a332a341184f4ad3b8cf257d9004ee8b |
| Source note | uspto-grants-2011_04 |