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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2075107Generated: November 2, 2026

Methyl iodide → HCID 58968720, compound

https://huagongshe.com/reaction/2075107

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl iodideHCID 6328—
ReactantBenzonitrile, 4-(trifluoromethyl)-HCID 67995—
ReactantHCID 58968691HCID 58968691—
ReactantHCID 178418443HCID 178418443—
ReactantHCID 178419651HCID 178419651—
ProductHCID 58968720HCID 58968720—

Reaction Steps

This compound was prepared by an analogous series of reactions to that used for the preparation of N-(2-(1-cyclopentyl-2-methoxypropan-2-yl)-5-(trifluoromethyl)benzyl)-N-(3,5-bis(trifluoromethyl)benzyl)-2-methyl-2H-tetrazol-5-amine from 2-((3,5-bis(trifluoromethyl)benzyl)(2-methyl-2H-tetrazole-5-yl)amino)methyl)-4-(trifluoromethyl)benzonitrile by the addition of cyclohexylmagnesium bromide followed by ethylmagnesium bromide then alkylation with methyl iodide. LC-MS calc 637.5, found 638.5 (M+H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07919506B2
Source datasetuspto-grants-2011_04
ORD IDord-a332a341184f4ad3b8cf257d9004ee8b
Source noteuspto-grants-2011_04