Tetrahydrofuran → N-[2-(3-bromo-4-methoxyphenyl)ethyl]-5-isopropyl-N-[4-(trifluoromethoxy)benzyl]pyrimidin-2-amine
Reaction equation
[Br:1][c:2]1[cH:3][c:4]([CH2:10][CH2:11][NH:12][c:13]2[n:14][cH:15][c:16]([CH:19]([CH3:20])[CH3:21])[cH:17][n:18]2)[cH:5][cH:6][c:7]1[O:8][CH3:9].[CH2:35]1[O:36][CH2:37][CH2:38][CH2:39]1.[F:22][C:23]([O:24][c:25]1[cH:26][cH:27][c:28]([CH2:29][Br:30])[cH:31][cH:32]1)([F:33])[F:34]>>[Br:1][c:2]1[cH:3][c:4]([CH2:10][CH2:11][N:12]([c:13]2[n:14][cH:15][c:16]([CH:19]([CH3:20])[CH3:21])[cH:17][n:18]2)[CH2:29][c:28]2[cH:27][cH:26][c:25]([O:24][C:23]([F:22])([F:33])[F:34])[cH:32][cH:31]2)[cH:5][cH:6][c:7]1[O:8][CH3:9]Participants
4
Sources & evidence
- ORD record
- ord-4e5c0b9dfb1646c69bf01d3e53ea6e8e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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