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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2075182Generated: October 31, 2026

Methanol → Ethyl 1-(4-bromo-3-fluorobenzyl)azetidine-3-carboxylate

https://huagongshe.com/reaction/2075182

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethanolHCID 887—
ReactantMethyl 1-(4-bromo-3-fluorobenzyl)azetidine-3-carboxylateHCID 59651823—
ProductEthyl 1-(4-bromo-3-fluorobenzyl)azetidine-3-carboxylateHCID 58415312—

Reaction Steps

Synthesized in an analogous fashion as methyl 1-(4-bromo-3-fluorobenzyl)azetidine-3-carboxylate, but MeOH from step 1 was removed and EtOH was used for step 2. MS (ESI) m/z: Calculated: 315.0; Observed: 316.0 (M++1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07919519B2
Source datasetuspto-grants-2011_04
ORD IDord-bc425bd5c7644e62b713f18be6616752
Source noteuspto-grants-2011_04