Benzoylhydrazine → 2-(Chloromethyl)-5-phenyl-1,3,4-oxadiazole

HRID 2075551Notes

Reaction equation

HRID 2075551 reaction equation
[Cl:1][C:2]1C=CC2SC(CCl)=NC=2[CH:12]=1.[C:13]([NH:21][NH2:22])(=[O:20])[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1>>[Cl:1][CH2:2][C:12]1[O:20][C:13]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)=[N:21][N:22]=1

Participants

3

Reactant 2

HCID 11955BenzoylhydrazineHCID 107988395-chloro-2-(chloromethyl)-1,3-benzothiazole

Product 1

HCID 3149412-(Chloromethyl)-5-phenyl-1,3,4-oxadiazole

Procedure

2-Chloromethyl-5-phenyl-[1,3,4]oxadiazole was prepared similarly to 5-chloro-2-chloromethyl-benzothiazole using benzoic acid hydrazide as the reagent.

Sources & evidence

ORD record
ord-814d7fee68aa441c89394cf4862b1325
Source dataset
uspto-grants-2011_04
Patent number
US07919628B2

Reaction notes

Loading…