Hydrogen Peroxide → HCID 58926503, compound

HRID 2075701Notes

Reaction equation

HRID 2075701 reaction equation
[Br:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[N:8]1[C:12]([C:15]3[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=3)=[N:13][N:14]=[C:7]1[CH:6]=[N:5]2.[OH:21]O.O>C(O)(=O)C>[Br:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[N:8]1[C:12]([C:15]3[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=3)=[N:13][N:14]=[C:7]1[C:6](=[O:21])[NH:5]2

Participants

5

Reactant 3

HCID 784Hydrogen PeroxideHCID 962WaterHCID 58926527HCID 58926527, compound

Product 1

HCID 58926503HCID 58926503, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Conditions

Temperature
50 °C

Procedure

7-Bromo-1-phenyl-[1,2,4]triazolo[4,3-a]quinoxaline (279 mg, 0.86 mmol) was dissolved in acetic acid (7.5 mL). Hydrogen peroxide (30%, 2.5 mL) was added, and the reaction was heated to 50° C. overnight. The reaction was poured into water (25 mL) and stirred at room temperature for 2 hours. The precipitate was filtered, washed with water, and dried to obtain the desired product, 5z.

Workup

  1. filtrationThe precipitate was filtered
  2. washwashed with water
  3. customdried

Sources & evidence

ORD record
ord-885943f5a6ff42688301110badba2286
Source dataset
uspto-grants-2011_04
Patent number
US07919621B2

Reaction notes

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