HCID 67095819, compound → HCID 57780696, compound

HRID 2076052Notes

Reaction equation

HRID 2076052 reaction equation
CN(C)[CH:3]=[C:4]1[C:9](=O)[CH:8]([C:11]2[CH:16]=[CH:15][C:14]([Cl:17])=[C:13]([Cl:18])[CH:12]=2)[CH2:7][CH2:6][CH2:5]1.[N+]([O-])(O)=O.[N+]([O-])(O)=O.[CH3:28][O:29][C:30]1[CH:31]=[C:32]([NH:42][C:43]([NH2:45])=[NH:44])[CH:33]=[CH:34][C:35]=1[N:36]1[CH:40]=[C:39]([CH3:41])[N:38]=[CH:37]1>>[Cl:18][C:13]1[CH:12]=[C:11]([CH:8]2[C:9]3[N:45]=[C:43]([NH:42][C:32]4[CH:33]=[CH:34][C:35]([N:36]5[CH:40]=[C:39]([CH3:41])[N:38]=[CH:37]5)=[C:30]([O:29][CH3:28])[CH:31]=4)[N:44]=[CH:3][C:4]=3[CH2:5][CH2:6][CH2:7]2)[CH:16]=[CH:15][C:14]=1[Cl:17]

Participants

3

Reactant 2

HCID 67095819HCID 67095819, compoundHCID 178493228HCID 178493228, compound

Product 1

HCID 57780696HCID 57780696, compound

Procedure

The title compound was prepared from 6-[1-dimethylamino-methylidene]-2-(3,4-dichloro-phenyl)-cyclohexanone (119 mg, 0.40 mmol) and N-[3-methoxy-4-(4-methyl-imidazol-1-yl)-phenyl]-guanidine dinitrate (148 mg, 0.40 mmol) using in analogous manner the procedure described in example 45b). Obtained as an off-white solid (92 mg, 48%). MS ISP (m/e): 480.0 [(M+H)+]. mp 167-169° C.

Sources & evidence

ORD record
ord-d84395df884048c095a9dbd3a57510f0
Source dataset
uspto-grants-2011_04
Patent number
US07923450B2

Reaction notes

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