HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-Butoxy bis(dimethylamino)methane → [1-(4-Chloro-phenyl)-3-[1-dimethylamino-methylidene]-2-oxo-cyclohexyl]-acetonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-Butoxy bis(dimethylamino)methane | HCID 79885 | — |
| Reactant | [1-(4-Chlorophenyl)-2-oxo-cyclohexyl]-acetonitrile | HCID 68911510 | — |
| Product | [1-(4-Chloro-phenyl)-3-[1-dimethylamino-methylidene]-2-oxo-cyclohexyl]-acetonitrile | HCID 67096051 | — |
Reaction Steps
[1-(4-Chlorophenyl)-2-oxo-cyclohexyl]-acetonitrile (101 mg, 0.43 mmol) was reacted with tert.-butoxy-bis-(dimethylamino)-methane using in analogous manner the procedure described in example 45a) to give crude title compound (149 mg) as a red oil which was used directly in the next step.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07923450B2 |
| Source dataset | uspto-grants-2011_04 |
| ORD ID | ord-8ba4e7165850462189fcbaed7dafea47 |
| Source note | uspto-grants-2011_04 |