HCID 67095891, compound → HCID 57780708, compound

HRID 2076068Notes

Reaction equation

HRID 2076068 reaction equation
CN(C)[CH:3]=[C:4]1[CH2:9][O:8][CH2:7][CH:6]([C:10]([O:12][CH3:13])=[O:11])[C:5]1=O.[N+]([O-])(O)=O.[N+]([O-])(O)=O.[CH3:24][O:25][C:26]1[CH:27]=[C:28]([NH:38][C:39]([NH2:41])=[NH:40])[CH:29]=[CH:30][C:31]=1[N:32]1[CH:36]=[C:35]([CH3:37])[N:34]=[CH:33]1>>[CH3:24][O:25][C:26]1[CH:27]=[C:28]([NH:38][C:39]2[N:41]=[CH:3][C:4]3[CH2:9][O:8][CH2:7][CH:6]([C:10]([O:12][CH3:13])=[O:11])[C:5]=3[N:40]=2)[CH:29]=[CH:30][C:31]=1[N:32]1[CH:36]=[C:35]([CH3:37])[N:34]=[CH:33]1

Participants

3

Reactant 2

HCID 67095891HCID 67095891, compoundHCID 178493228HCID 178493228, compound

Product 1

HCID 57780708HCID 57780708, compound

Procedure

The title compound was prepared from crude methyl 5-[1-dimethylamino-methylidene]-4-oxo-tetrahydro-pyran-3-carboxylate (97 mg, 0.45 mmol) and N-[3-methoxy-4-(4-methyl-imidazol-1-yl)-phenyl]-guanidine dinitrate (114 mg, 0.31 mmol) using in analogous manner the procedure described in example 45b). Obtained as a pale-yellow oil (8 mg, 7%). MS ISP (m/e): 396.4 [(M+H)+].

Sources & evidence

ORD record
ord-4c47b7105b1c4b61ac8927d9345d8845
Source dataset
uspto-grants-2011_04
Patent number
US07923450B2

Reaction notes

Loading…