HCID 67096148, compound → HCID 57780705, compound

HRID 2076121Notes

Reaction equation

HRID 2076121 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([NH:15][C:16]([NH2:18])=[S:17])[CH:6]=[CH:7][C:8]=1[N:9]1[CH:13]=[C:12]([CH3:14])[N:11]=[CH:10]1.Br[CH:20]1[CH2:25][CH2:24][CH2:23][CH:22]([C:26]2[O:30][N:29]=[C:28]([CH3:31])[N:27]=2)[C:21]1=O>>[CH3:1][O:2][C:3]1[CH:4]=[C:5]([NH:15][C:16]2[S:17][C:20]3[CH2:25][CH2:24][CH2:23][CH:22]([C:26]4[O:30][N:29]=[C:28]([CH3:31])[N:27]=4)[C:21]=3[N:18]=2)[CH:6]=[CH:7][C:8]=1[N:9]1[CH:13]=[C:12]([CH3:14])[N:11]=[CH:10]1

Participants

3

Reactant 2

HCID 67096148HCID 67096148, compoundHCID 71650841[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]thiourea

Product 1

HCID 57780705HCID 57780705, compound

Procedure

The title compound was prepared from [3-methoxy-4-(4-methyl-imidazol-1-yl)-phenyl]-thiourea (70 mg, 0.27 mmol) and crude 2-bromo-6-(3-methyl-[1,2,4]oxadiazol-5-yl)-cyclohexanone (173 mg, ca. 0.5 mmol) using in analogous manner the procedure described in example 1b). Obtained as a light-brown foam (25 mg, 22%). MS ISP (m/e): 423.1 (100) [(M+H)+].

Sources & evidence

ORD record
ord-464e7d2d55ac4f7da4ad5392fcdf20bc
Source dataset
uspto-grants-2011_04
Patent number
US07923450B2

Reaction notes

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