Methyl 2-(4-bromophenyl)acetate → HCID 67119171, compound

Participants

Reaction Steps

According to a method similar to Example (8-1), from tert-butyl 2-{[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy]methyl}-5-(trifluoromethyl)benzoate (100 mg, 0.21 mmol) obtained in Example (2-4) and methyl (4-bromophenyl)acetate (62 mg, 0.27 mmol) obtained in Example (3-1), tert-butyl 2-[({4′-[(methoxycarbonyl)methyl]-1,1′-biphenyl-4-yl}oxy)methyl]-5-(trifluoromethyl)benzoate was obtained (54 mg, yield: 52%).

Provenance & Evidence