N-(3-iodophenyl)methanesulfonamide → tert-Butyl 2-hydroxy-6-[({3'-[(methylsulfonyl)amino]-1,1'-biphenyl-4-yl}oxy)methyl]-3-(trifluromethyl)benzoate

Participants

Reaction Steps

According to a method similar to Example (31), from N-(3-iodophenyl)methanesulfonamide (134 mg, 0.45 mmol) obtained in Example (35-1) and tert-butyl 2-hydroxy-6-{[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy]methyl}-3-(trifluoromethyl)benzoate (250 mg, 0.51 mmol) obtained in Example (22-4), the title compound was obtained as a pale violet powder (20 mg, yield: 8%).

Provenance & Evidence