HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tert-butyl 6-(bromomethyl)-3-methoxy-2-(methoxymethyl)benzoate → Tert-butyl 3-methoxy-2-(methoxymethoxy)-6-[({4'-[(methoxycarbonyl)methyl]-1,1'-biphenyl-4-yl}oxy)methyl]benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tert-butyl 6-(bromomethyl)-3-methoxy-2-(methoxymethyl)benzoate | HCID 67119266 | — |
| Reactant | Methyl (4'-hydroxy-1,1'-biphenyl-4-yl)acetate | HCID 86088038 | — |
| Product | Tert-butyl 3-methoxy-2-(methoxymethoxy)-6-[({4'-[(methoxycarbonyl)methyl]-1,1'-biphenyl-4-yl}oxy)methyl]benzoate | HCID 67119264 | 25% |
Reaction Steps
According to a method similar to Example (40-2), from tert-butyl 6-(bromomethyl)-3-methoxy-2-(methoxymethyl)benzoate (1.20 g, 2.33 mmol) and methyl (4′-hydroxy-1,1′-biphenyl-4-yl)acetate (619 mg, 2.56 mmol) obtained in Example (6-2), tert-butyl 3-methoxy-2-(methoxymethoxy)-6-[({4′-[(methoxycarbonyl)methyl]-1,1′-biphenyl-4-yl}oxy)methyl]benzoate was obtained (306 mg, yield: 25%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07923573B2 |
| Source dataset | uspto-grants-2011_04 |
| ORD ID | ord-f0cf1297028d405784475f47162fbe4c |
| Source note | uspto-grants-2011_04 |