1,1,1-Trifluoro-2-propanol → HCID 86617423, compound

Participants

Reaction Steps

According to a method similar to Example (72-1) and Example (13-5), from 2-(allyloxy)-6-{[(4′-{[(allyloxy)carbonyl]methyl}-1,1′-biphenyl-4-yl)oxy]methyl}-3-(trifluoromethyl)benzoic acid (150 mg, 0.29 mmol) and 1,1,1-trifluoro-2-propanol (31 μl, 0.34 mmol), the title compound was obtained as a yellow crystal (68 mg, two-step total yield: 43%).

Provenance & Evidence