反应详情

温度

100 °C

In a 300 mL three-necked flask were placed 19 g (60 mmol) of N′-benzoyl-4-bromobenzohydrazide and 100 mL of phosphoryl chloride. This mixture was stirred while being heated at 100° C. for 5 hours under a stream of nitrogen. After a predetermined time, the solid obtained by distilling off phosphoryl chloride from the mixture under reduced pressure was washed with a saturated aqueous sodium carbonate solution. The mixture was collected by suction filtration, and the collected solid was washed with methanol, so that 6.0 g of a white powder, which was a target substance, was obtained at a yield of 33%.

1. customIn a 300 mL three-necked flask were placed
2. customAfter a predetermined time, the solid obtained
3. distillationby distilling off phosphoryl chloride from the mixture under reduced pressure
4. washwas washed with a saturated aqueous sodium carbonate solution
5. filtrationThe mixture was collected by suction filtration
6. washthe collected solid was washed with methanol, so that 6.0 g of a white powder, which
7. customwas obtained at a yield of 33%