Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2076798Generated: October 30, 2026

Ethanolamine → (S)-2-(2-Hydroxy-ethylamino)-1-phenyl-ethanol

https://huagongshe.com/reaction/2076798

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthanolamineHCID 700—
Reactant(S)-styrene oxideHCID 114946—
SolventWaterHCID 962—
Product(S)-2-(2-Hydroxy-ethylamino)-1-phenyl-ethanolHCID 57849522—

Reaction Steps

5 g of (S)-(+)-styrene oxide and 15.410 mL ethanol amine were stirred at room temperature overnight. The solution is poured into water and the water was extracted with dichloromethane. The combined dichloromethane layers were washed with brine and concentrated in vacuo. The oil was used crude. Assumed quantitative yield carried on to the next step. Theoretical wt: 7.9 g

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07928103B2
Source datasetuspto-grants-2011_04
ORD IDord-6af10f9895bb4110aeae49ccecd52fb2
Source noteuspto-grants-2011_04