HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Phenylethane-1-sulfonyl chloride → 2-Phenyl-ethanesulfonic acid (4-oxo-3,4-dihydro-pyrimido[4,5-d]pyrimidin-2-ylmethyl)-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Phenylethane-1-sulfonyl chloride | HCID 2760374 | — |
| Reactant | HCID 136366828 | HCID 136366828 | — |
| Product | 2-Phenyl-ethanesulfonic acid (4-oxo-3,4-dihydro-pyrimido[4,5-d]pyrimidin-2-ylmethyl)-amide | HCID 135923550 | — |
Reaction Steps
In analogy to the procedure described in example 20.4, 2-aminomethyl-3H-pyrimido[4,5-d]pyrimidin-4-one (example 20.3) was treated with 2-phenyl-ethanesulfonyl chloride [4025-71-2] to obtain 2-phenyl-ethanesulfonic acid (4-oxo-3,4-dihydro-pyrimido[4,5-d]pyrimidin-2-ylmethyl)-amide as light brown solid. MS: m/e=346.3 [M+H+].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07928106B2 |
| Source dataset | uspto-grants-2011_04 |
| ORD ID | ord-8b969d85a39e4a61a31557f80d1956d9 |
| Source note | uspto-grants-2011_04 |