HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 67097843, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 2-benzyl-6,7,8,9-tetrahydro-5H-pyriMido[4,5-d]azepine | HCID 25070582 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 67097843 | HCID 67097843 | — |
Reaction Steps
2-Benzyl-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepine of Example 54 (415 mg, 1.73 mmol) was dissolved in dioxane (5 ml) and treated with 4 M HCl in dioxane (1 ml) and stirred overnight. The dioxane was decanted off and the residue washed with ether and then dried in vacuo to give the pure product as a colourless solid. (430 mgs, 74.7%)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07928099B2 |
| Source dataset | uspto-grants-2011_04 |
| ORD ID | ord-64f766ebc0114485bd7a3feabd6fb111 |
| Source note | uspto-grants-2011_04 |