HCID 59312356, compound → HCID 59312271, compound

HRID 2077040Notes

Reaction equation

HRID 2077040 reaction equation
[CH2:1]([C:8]1[N:9]=[C:10]([CH3:26])[C:11]2[CH2:17][CH2:16][N:15](CC3C=CC=CC=3)[CH2:14][CH2:13][C:12]=2[N:25]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1>[Pd]>[CH2:1]([C:8]1[N:9]=[C:10]([CH3:26])[C:11]2[CH2:17][CH2:16][NH:15][CH2:14][CH2:13][C:12]=2[N:25]=1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 1

HCID 59312356HCID 59312356, compound

Product 1

HCID 59312271HCID 59312271, compoundYield 90%

Reagents, catalysts & solvents 1

HCID 23938PalladiumCatalyst

Procedure

The title compound was prepared according to a similar method to that of Example 64, except that 10% palladium on carbon was used, starting from 2,7-dibenzyl-4-methyl-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepine of Preparation 39, and obtained as a pale yellow solid in 90% yield (44 mg).

Workup

  1. customobtained as a pale yellow solid in 90% yield (44 mg)

Sources & evidence

ORD record
ord-8a95aa57741442aba788b27d3dc34c86
Source dataset
uspto-grants-2011_04
Patent number
US07928099B2

Reaction notes

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