HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzeneethanimidamide → Tert-butyl 2-benzyl-9-methyl-4-oxo-3,4,5,6,8,9-hexahydro-7H-pyrimido[4,5-d]azepine-7-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzeneethanimidamide | HCID 27787 | — |
| Reactant | 1-Tert-butyl 4-ethyl 6-methyl-5-oxoazepane-1,4-dicarboxylate | HCID 59312224 | — |
| Product | Tert-butyl 2-benzyl-9-methyl-4-oxo-3,4,5,6,8,9-hexahydro-7H-pyrimido[4,5-d]azepine-7-carboxylate | HCID 136058087 | 70% |
Reaction Steps
The title compound was prepared by a similar method to that of Preparation 1, Step A, starting from 1-tert-butyl 4-ethyl 6-methyl-5-oxoazepane-1,4-dicarboxylate and 2-phenyl-acetamidine, yielding 70% of title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07928099B2 |
| Source dataset | uspto-grants-2011_04 |
| ORD ID | ord-e7cb177616d94d0fa3a9b1e1692cbbc8 |
| Source note | uspto-grants-2011_04 |