Guaiacol → HCID 67110132, compound

HRID 2077163Notes

Reaction equation

HRID 2077163 reaction equation
[CH3:1][O:2][C:3]([C:5]1[N:6]=[CH:7][C:8]2[C:13]([C:14]=1[OH:15])=[CH:12][CH:11]=[CH:10][C:9]=2I)=[O:4].[CH3:17][O:18][C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][C:20]=1[OH:25]>>[CH3:1][O:2][C:3]([C:5]1[N:6]=[CH:7][C:8]2[C:13]([C:14]=1[OH:15])=[CH:12][CH:11]=[CH:10][C:9]=2[O:25][C:20]1[CH:21]=[CH:22][CH:23]=[CH:24][C:19]=1[O:18][CH3:17])=[O:4]

Participants

3

Reactant 2

HCID 460GuaiacolHCID 67110147Methyl 4-hydroxy-8-iodoisoquinoline-3-carboxylate

Product 1

HCID 67110132HCID 67110132, compound

Procedure

The title compound was synthesized from 4-hydroxy-8-iodo-isoquinoline-3-carboxylic acid methyl ester and 2-methoxy-phenol in analogy to example 19d; MS-(+)-ion: M+1=326.4.

Sources & evidence

ORD record
ord-a0ef7d3b78fe4869b09faf6b48344238
Source dataset
uspto-grants-2011_04
Patent number
US07928120B2

Reaction notes

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