HuagongsheHuagongshe Chemistry Print Report · For research reference only
5,7-Dichlorobenzofuran → (RS)-2-[1-(5,7-Dichloro-benzofuran-2-yl)-methanoyl]-4-methyl-piperazine-1-carboxylic acid tert-butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5,7-Dichlorobenzofuran | HCID 90014 | — |
| Reactant | (RS)-2-(methoxy-methyl-carbamoyl)4-methyl-piperazine-1-carboxylic acid dimethyl-ethyl ester | HCID 86625772 | — |
| Product | (RS)-2-[1-(5,7-Dichloro-benzofuran-2-yl)-methanoyl]-4-methyl-piperazine-1-carboxylic acid tert-butyl ester | HCID 66968136 | — |
Reaction Steps
The title compound (0.94 g) was prepared from (RS)-2-(methoxy-methyl-carbamoyl)-4-methyl-piperazine-1-carboxylic acid dimethyl-ethyl ester, D54 (1.00 g) and 5,7-dichloro-benzofuran (0.65 g, FP1.537.206) using the method of Description 2.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07928124B2 |
| Source dataset | uspto-grants-2011_04 |
| ORD ID | ord-7f180e0e62564534bd22ad48bdb13578 |
| Source note | uspto-grants-2011_04 |