Dimethyl Sulfoxide → Methyl 6-(((3-butyl-5-methylisoxazol-4-yl)methyl)amino)nicotinate

HRID 207737Notes

Reaction equation

HRID 207737 reaction equation
[CH2:1]([CH2:2][CH2:3][CH3:4])[c:5]1[n:6][o:7][c:8]([CH3:12])[c:9]1[CH2:10][NH2:11].[CH3:33][S:34]([CH3:35])=[O:36].[CH:24]([N:25]([CH2:26][CH3:27])[CH:28]([CH3:29])[CH3:30])([CH3:31])[CH3:32].[Cl:13][c:14]1[n:15][cH:16][c:17]([C:18](=[O:19])[O:20][CH3:21])[cH:22][cH:23]1>>[CH2:1]([CH2:2][CH2:3][CH3:4])[c:5]1[n:6][o:7][c:8]([CH3:12])[c:9]1[CH2:10][NH:11][c:14]1[n:15][cH:16][c:17]([C:18](=[O:19])[O:20][CH3:21])[cH:22][cH:23]1

Participants

5

Reactant 4

HCID 679Dimethyl SulfoxideHCID 81531DiisopropylethylamineHCID 254249Methyl 6-chloropyridine-3-carboxylateHCID 66643513C-(3-Butyl-5-methyl-isoxazol-4-yl)-methylamine

Product 1

HCID 66643788Methyl 6-(((3-butyl-5-methylisoxazol-4-yl)methyl)amino)nicotinate

Sources & evidence

ORD record
ord-16b3528cc6e04ea49f6599217efeba71
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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