Acetic Anhydride → HCID 57584954, compound

HRID 2077546Notes

Reaction equation

HRID 2077546 reaction equation
[NH2:1][C:2]1[S:3][C:4]2[CH:10]=[C:9]([C:11]3[O:15][C:14]([NH:16][S:17]([C:20]4[CH:25]=[CH:24][C:23]([F:26])=[CH:22][CH:21]=4)(=[O:19])=[O:18])=[N:13][N:12]=3)[CH:8]=[CH:7][C:5]=2[N:6]=1.[CH3:27][C:28](OC(C)=O)=[O:29]>CN(C1C=CN=CC=1)C.N1C=CC=CC=1>[F:26][C:23]1[CH:22]=[CH:21][C:20]([S:17]([NH:16][C:14]2[O:15][C:11]([C:9]3[CH:8]=[CH:7][C:5]4[N:6]=[C:2]([NH:1][C:28](=[O:29])[CH3:27])[S:3][C:4]=4[CH:10]=3)=[N:12][N:13]=2)(=[O:18])=[O:19])=[CH:25][CH:24]=1

Participants

5

Reactant 2

HCID 7918Acetic AnhydrideHCID 57585142HCID 57585142, compound

Product 1

HCID 57584954HCID 57584954, compound

Reagents, catalysts & solvents 2

HCID 142844-(Dimethylamino)pyridineCatalystHCID 1049PyridineSolvent

Procedure

A mixture of N-(5-(2-aminobenzo[d]thiazol-6-yl)-1,3,4-oxadiazol-2-yl)-4-fluorobenzenesulfonamide, pyridine, Ac2O, and DMAP, was stirred at rt for 4 h. The product was isolated following standard procedures. MS (ESI pos. ion) m/z: calk's for C17H12FN5O4S2: 433.0. found: 434.0 (MH+).

Workup

  1. customThe product was isolated

Sources & evidence

ORD record
ord-2d5128d279e843b0a2ad191f85b60c2a
Source dataset
uspto-grants-2011_04
Patent number
US07928140B2

Reaction notes

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