Dansylamide → HCID 21876494, compound

HRID 2077783Notes

Reaction equation

HRID 2077783 reaction equation
[C:1](=[O:34])(OC1C=CC=CC=1)[O:2][CH2:3][CH2:4][C:5]1[CH:10]=[CH:9][C:8]([N:11]2[C:15]3[CH:16]=[C:17]([Cl:24])[C:18]([C:20]([F:23])([F:22])[F:21])=[CH:19][C:14]=3[N:13]=[C:12]2[CH2:25][CH3:26])=[CH:7][CH:6]=1.[CH3:35][N:36]([CH3:51])[C:37]1[CH:46]=[CH:45][CH:44]=[C:43]2[C:38]=1[CH:39]=[CH:40][CH:41]=[C:42]2[S:47]([NH2:50])(=[O:49])=[O:48]>>[Cl:24][C:17]1[C:18]([C:20]([F:23])([F:22])[F:21])=[CH:19][C:14]2[N:13]=[C:12]([CH2:25][CH3:26])[N:11]([C:8]3[CH:7]=[CH:6][C:5]([CH2:4][CH2:3][O:2][C:1](=[O:34])[NH:50][S:47]([C:42]4[C:43]5[C:38](=[C:37]([N:36]([CH3:51])[CH3:35])[CH:46]=[CH:45][CH:44]=5)[CH:39]=[CH:40][CH:41]=4)(=[O:48])=[O:49])=[CH:10][CH:9]=3)[C:15]=2[CH:16]=1

Participants

3

Reactant 2

HCID 65077DansylamideHCID 218764092-{4-[6-chloro-2-ethyl-5-(trifluoromethyl)-1H-benzimidazol-1-yl]phenyl}ethyl phenyl carbonate

Product 1

HCID 21876494HCID 21876494, compound

Procedure

The title compound was prepared according to the procedure described in step 2 of Example 243 from 2-{4-[6-chloro-2-ethyl-5-(trifluoromethyl)-1H-benzimidazol-1-yl]phenyl}ethyl phenyl carbonate and 5-(dimethylamino)-1-naphthylsulfonamide.

Sources & evidence

ORD record
ord-7ebe5085ccf344119d936680d90435d3
Source dataset
uspto-grants-2011_04
Patent number
US07928119B2

Reaction notes

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