Thionyl Chloride → 2-(3-Chlorophenyl)-2-methylpropanoyl chloride

HRID 2078154Notes

Reaction equation

HRID 2078154 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([C:8]([CH3:13])([CH3:12])[C:9](O)=[O:10])[CH:5]=[CH:6][CH:7]=1.S(Cl)([Cl:16])=O>>[Cl:1][C:2]1[CH:3]=[C:4]([C:8]([CH3:13])([CH3:12])[C:9]([Cl:16])=[O:10])[CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 24386Thionyl ChlorideHCID 155826442-(3-Chlorophenyl)-2-methylpropanoic acid

Product 1

HCID 139875312-(3-Chlorophenyl)-2-methylpropanoyl chloride

Procedure

2-(3-Chlorophenyl)-2-methylpropanoic acid (5.7 g, 28.7 mmol) was stirred in thionyl chloride (100 mL) for 2 hours at reflux. The thionyl chloride was removed under vacuum to give the product (5.69 g).

Workup

  1. temperatureat reflux
  2. customThe thionyl chloride was removed under vacuum

Sources & evidence

ORD record
ord-e875b7ed7d81462790be6475de18cdd0
Source dataset
uspto-grants-2011_04
Patent number
US07928139B2

Reaction notes

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