HRID2078968

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID6328

Methyl iodide

CH3I

HCID24758

Sodium hydride

HNa

结构：CC(C)(C)OC(=O)N(c1cc2c(cn1)-c1sc(C(=O)Nc3ccccc3Cl)cc1CCO2)C(C)(C)C

HCID57900446

未命名化合物

PRODUCTS

生成物

结构：CN(C(=O)c1cc2c(s1)-c1cnc(N(C(=O)OC(C)(C)C)C(C)(C)C)cc1OCC2)c1ccccc1Cl

HCID57900249

未命名化合物

收率 78%

PROCEDURE

实验过程

Following Scheme 4, tert-butyl tert-butyl(2-(2-chlorophenylcarbamoyl)-4,5-dihydropyrido[4,3-b]thieno[2,3-d]oxepin-8-yl)carbamate, methyl iodide and sodium hydride were reacted to give tert-butyl tert-butyl(2-((2-chlorophenyl)(methyl)carbamoyl)-4,5-dihydropyrido[4,3-b]thieno[2,3-d]oxepin-8-yl)carbamate (78%). MS: (ESI+) 542.3

WORKUP

后处理

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