2,4-Difluoroaniline → HCID 57900511, compound

HRID 2079062Notes

Reaction equation

HRID 2079062 reaction equation
[Br:1][C:2]1[CH:11]=[CH:10][C:9]2[O:8][CH2:7][C:6]3[CH:12]=[C:13]([C:15](Cl)=[O:16])[S:14][C:5]=3[C:4]=2[CH:3]=1.[F:18][C:19]1[CH:25]=[C:24]([F:26])[CH:23]=[CH:22][C:20]=1[NH2:21]>>[Br:1][C:2]1[CH:11]=[CH:10][C:9]2[O:8][CH2:7][C:6]3[CH:12]=[C:13]([C:15]([NH:21][C:20]4[CH:22]=[CH:23][C:24]([F:26])=[CH:25][C:19]=4[F:18])=[O:16])[S:14][C:5]=3[C:4]=2[CH:3]=1

Participants

3

Reactant 2

HCID 97092,4-DifluoroanilineHCID 579004048-bromo-4H-thieno[3,2-c]chromene-2-carbonyl chloride

Product 1

HCID 57900511HCID 57900511, compound

Procedure

8-Bromo-4H-thieno[3,2-c]chromene-2-carbonyl chloride 4bp is reacted with 2,4-difluoroaniline to give 5bp, as in General Procedure B-bp.

Workup

  1. customto give 5bp, as in General Procedure B-bp

Sources & evidence

ORD record
ord-a871a4a780c042d69c9a8040223ec49e
Source dataset
uspto-grants-2011_04
Patent number
US07928248B2

Reaction notes

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