Ethyl Spiro[2.5]octane-1-carboxylate → HCID 11820440, compound

HRID 2079482Notes

Reaction equation

HRID 2079482 reaction equation
[CH3:1][C:2]1([CH3:17])[CH2:14][C:13]([CH3:16])([CH3:15])[CH2:12][C:4]2([CH:6]([C:7]([O:9]CC)=[O:8])[CH2:5]2)[CH2:3]1.C1(C(OCC)=O)C2(CCCCC2)C1>>[CH3:1][C:2]1([CH3:17])[CH2:14][C:13]([CH3:16])([CH3:15])[CH2:12][C:4]2([CH:6]([C:7]([OH:9])=[O:8])[CH2:5]2)[CH2:3]1

Participants

3

Reactant 2

HCID 11206164Ethyl Spiro[2.5]octane-1-carboxylateHCID 67102506HCID 67102506, compound

Product 1

HCID 11820440HCID 11820440, compound

Procedure

The title compound was prepared as described in Example 1B substituting the product from Example 52B for the product from Example 1A. 1H NMR (DMSO-d6, 300 MHz) δ 1.34-1.43 (m, 3H), 1.11-1.19 (m, 4H), 0.95 (s, 3H), 0.93 (s, 3H), 0.92 (s, 3H), 0.87 (m, 1H), 0.85 (s, 3H), 0.82 (dd, J=4.0, 7.9 Hz, 1H); 13C NMR (DMSO-d6, 100 MHz) δ 19.3, 24.9, 25.7, 30.7, 30.9, 31.2, 31.5, 32.0, 32.4, 40.1, 48.7, 51.9, 173.2.

Sources & evidence

ORD record
ord-e12cee843bdd42ed8738d6074973771e
Source dataset
uspto-grants-2011_04
Patent number
US07932245B2

Reaction notes

Loading…