N-Cyclohexyl-3-(phenylmethoxy)benzeneethanamine → HCID 67103142, compound

HRID 2079581Notes

Reaction equation

HRID 2079581 reaction equation
C([O:8][C:9]1[CH:10]=[C:11]([CH2:15][CH2:16][NH:17][CH:18]2[CH2:23][CH2:22][CH2:21][CH2:20][CH2:19]2)[CH:12]=[CH:13][CH:14]=1)C1C=CC=CC=1.[H][H]>C(O)C.[Pd]>[CH:18]1([NH:17][CH2:16][CH2:15][C:11]2[CH:10]=[C:9]([OH:8])[CH:14]=[CH:13][CH:12]=2)[CH2:19][CH2:20][CH2:21][CH2:22][CH2:23]1

Participants

5

Reactant 2

HCID 67103172N-Cyclohexyl-3-(phenylmethoxy)benzeneethanamineHCID 178418361HCID 178418361, compound

Product 1

HCID 67103142HCID 67103142, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

A stirred solution of the oil isolated in Step D (4.5 g, 14 mmol) and Pd/C (10%, 150 mg) in ethanol (100 mL) was hydrogenated under 1 atm of hydrogen overnight. The catalyst was filtered off, and the solvent was removed in vacuo to yield an oil.

Workup

  1. filtrationThe catalyst was filtered off
  2. customthe solvent was removed in vacuo
  3. customto yield an oil

Sources & evidence

ORD record
ord-a4cb920704af493a87189b8772a3e32b
Source dataset
uspto-grants-2011_04
Patent number
US07932261B2

Reaction notes

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