HRID2079661

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID577815

(4-Aminophenyl)(morpholin-4-yl)methanone

C11H14N2O2

HCID59199305

7-Bromo-2,5-dichloro-8-methoxyquinazoline

C9H5BrCl2N2O

PRODUCTS

生成物

结构：COc1c(Br)cc(Cl)c2cnc(Nc3ccc(C(=O)N4CCOCC4)cc3)nc12

HCID67102176

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID3776

Isopropanol

C3H8O

CONDITIONS

反应条件

温度: 90 °C

PROCEDURE

实验过程

To 7-bromo-2,5-dichloro-8-methoxyquinazoline (1 eq) was added (4-aminophenyl) (morpholino)methanone (1 eq) in isopropanol and the mixture was heated to 90° C. for 16 h. The solid formed was filtered to give (4-(7-bromo-5-chloro-8-methoxyquinazolin-2-ylamino)phenyl) (morpholino)methanone and was confirmed by LC/MS. ES/MS m/z 478 (MH+).

WORKUP

后处理

customThe solid formed
filtrationwas filtered