HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 2079661Erstellt: 25. Oktober 2026
4-(Morpholine-4-carbonyl)aniline → (4-(7-Bromo-5-chloro-8-methoxyquinazolin-2-ylamino)phenyl) (morpholino)methanone
https://huagongshe.com/reaction/2079661
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|
| Edukt | 4-(Morpholine-4-carbonyl)aniline | HCID 577815 | — |
| Edukt | 7-Bromo-2,5-dichloro-8-methoxyquinazoline | HCID 59199305 | — |
| Lösungsmittel | Isopropanol | HCID 3776 | — |
| Produkt | (4-(7-Bromo-5-chloro-8-methoxyquinazolin-2-ylamino)phenyl) (morpholino)methanone | HCID 67102176 | — |
Reaktionsschritte
To 7-bromo-2,5-dichloro-8-methoxyquinazoline (1 eq) was added (4-aminophenyl) (morpholino)methanone (1 eq) in isopropanol and the mixture was heated to 90° C. for 16 h. The solid formed was filtered to give (4-(7-bromo-5-chloro-8-methoxyquinazolin-2-ylamino)phenyl) (morpholino)methanone and was confirmed by LC/MS. ES/MS m/z 478 (MH+).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patentnummer | US07932262B2 |
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| Quelldatensatz | uspto-grants-2011_04 |
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| ORD ID | ord-16c0be6e54cb4baf87d33dcaf197801d |
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| Quellennotiz | uspto-grants-2011_04 |
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