1-Butanol → 5-Bromo-2-{4-[2-hydroxy-3-(N,N-dimethylamino)propoxy]anilino}-4-(indan-5-ylamino)pyrimidine
Reaction equation
[Br:17][c:18]1[c:19]([NH:25][c:26]2[cH:27][c:28]3[c:32]([cH:33][cH:34]2)[CH2:31][CH2:30][CH2:29]3)[n:20][c:21]([Cl:24])[n:22][cH:23]1.[CH2:37]([OH:38])[CH2:39][CH2:40][CH3:41].[CH3:35][OH:36].[ClH:1].[OH:2][CH:3]([CH2:4][O:5][c:6]1[cH:7][cH:8][c:9]([NH2:10])[cH:11][cH:12]1)[CH2:13][N:14]([CH3:15])[CH3:16]>>[OH:2][CH:3]([CH2:4][O:5][c:6]1[cH:7][cH:8][c:9]([NH:10][c:21]2[n:20][c:19]([NH:25][c:26]3[cH:27][c:28]4[c:32]([cH:33][cH:34]3)[CH2:31][CH2:30][CH2:29]4)[c:18]([Br:17])[cH:23][n:22]2)[cH:11][cH:12]1)[CH2:13][N:14]([CH3:15])[CH3:16]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-9933d15f44074937ad43c36dbe1e1f4b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
Loading…