HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Cyanophenylboronic acid → 4-(1-benzenesulfonyl-6-nitro-1H-indol-3-yl)-benzonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Cyanophenylboronic acid | HCID 2734326 | — |
| Reactant | 4-(1-isopropyl-6-nitro-1H-indol-3-yl)-benzonitrile | HCID 57442194 | — |
| Reactant | 1-benzenesulfonyl-3-bromo-6-nitro-1H-indole | HCID 57442196 | — |
| Product | 4-(1-benzenesulfonyl-6-nitro-1H-indol-3-yl)-benzonitrile | HCID 57442242 | — |
Reaction Steps
Prepare this compound from 1-benzenesulfonyl-3-bromo-6-nitro-1H-indole, 7, and 4-cyanophenylboronic acid using Method C described above for 4-(1-isopropyl-6-nitro-1H-indol-3-yl)-benzonitrile 5. Purify by precipitation from EtOAc/hexanes. 1H NMR (DMSO-d6) δ 8.78 (d, 1H, J=1.8 Hz), 8.73 (s, 1H), 8.17 (dd, 1H, J=2.2, 8.8 Hz), 8.14-8.11 (m, 2H), 8.07 (d, 1H, J=8.8 Hz), 7.97-7.92 (m, 4H), 7.72 (tt, 1H, J=1.3, 7.5 Hz), 7.63-7.59 (m, 2H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07932284B2 |
| Source dataset | uspto-grants-2011_04 |
| ORD ID | ord-547b9d45c3914d66bf2086dcbe9a3ce4 |
| Source note | uspto-grants-2011_04 |