HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl ketone → 2-(Dimethylamino)-2-ethylbutanenitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl ketone | HCID 7288 | — |
| Reactant | Potassium Cyanide | HCID 9032 | — |
| Reactant | Dimethylamine, hydrochloride | HCID 10473 | — |
| Reactant | 1-(Dimethylamino)cyclopentanecarbonitrile | HCID 10773049 | — |
| Solvent | Water | HCID 962 | — |
| Product | 2-(Dimethylamino)-2-ethylbutanenitrile | HCID 43802551 | 57.5% |
Reaction Steps
The title compound (8.05 g, 57.5%) was prepared from dimethylamine hydrochloride (8.154 g, 0.1 mol), 3-pentanone (8.61 g, 0.1 mol) and potassium cyanide (6.51 g, 0.1 mol) in water (50 ml) in a similar manner to that described in D1. 1H NMR (CDCl3) δ: 0.96 (6H, t, J=7.6 Hz), 1.67-1.90 (4H, m), 2.33 (6H, s).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07745642B2 |
| Source dataset | uspto-grants-2010_06 |
| ORD ID | ord-046db7f9d7834ae591be4a5502da87f3 |
| Source note | uspto-grants-2010_06 |