Trifluoroacetic acid → HCID 178477647, compound

HRID 2080681Notes

Reaction equation

[CH2:1]([S:3]([C:6]1[CH:39]=[CH:38][C:9]([O:10][C:11]2[C:12]([C:34]([O:36][CH3:37])=[O:35])=[CH:13][C:14]3[N:18]=[C:17]([C:19]4[CH:24]=[CH:23][CH:22]=[CH:21][N:20]=4)[N:16](COCC[Si](C)(C)C)[C:15]=3[CH:33]=2)=[CH:8][CH:7]=1)(=[O:5])=[O:4])[CH3:2].FC(F)(F)C(O)=O>>[CH2:1]([S:3]([C:6]1[CH:39]=[CH:38][C:9]([O:10][C:11]2[C:12]([C:34]([O:36][CH3:37])=[O:35])=[CH:13][C:14]3[N:18]=[C:17]([C:19]4[CH:24]=[CH:23][CH:22]=[CH:21][N:20]=4)[NH:16][C:15]=3[CH:33]=2)=[CH:8][CH:7]=1)(=[O:4])=[O:5])[CH3:2]

Participants

Reactant 2

HCID 6422Trifluoroacetic acid

HCID 57433543HCID 57433543, compound

Product 1

HCID 178477647HCID 178477647, compound

Procedure

Methyl 6-[4-(ethylsulfonyl)phenoxy]-2-(2-pyridinyl)-1-{[2-(trimethylsilyl)ethoxy]methyl}-1H-benzimidazole-5-carboxylate was reacted with trifluoroacetic acid to obtain the entitled compound.

Workup

customto obtain the entitled compound

Sources & evidence

ORD record: ord-6b94ab8fe3c74f3bb2dce7142373ac9f
Source dataset: uspto-grants-2011_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07932394B2

Reaction notes

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