Chloroform → HCID 57433662, compound

HRID 2080685Notes

Reaction equation

HRID 2080685 reaction equation
C(N(CC)CC)C.[CH3:8][S:9](Cl)(=[O:11])=[O:10].C(Cl)(Cl)Cl.[C:17]([O:20][CH:21]([CH2:26][CH2:27][OH:28])[C:22]([O:24][CH3:25])=[O:23])(=[O:19])[CH3:18]>O>[C:17]([O:20][CH:21]([CH2:26][CH2:27][O:28][S:9]([CH3:8])(=[O:11])=[O:10])[C:22]([O:24][CH3:25])=[O:23])(=[O:19])[CH3:18]

Participants

6

Reactant 4

HCID 6212ChloroformHCID 8471TriethylamineHCID 31297Methanesulfonyl chlorideHCID 57433661HCID 57433661, compound

Product 1

HCID 57433662HCID 57433662, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

In an ice bath, 6.1 ml of triethylamine and 2.3 ml of methanesulfonyl chloride were added to a chloroform (15 ml) solution of 2.59 g of methyl 2-(acetyloxy)-4-hydroxybutanoate, and stirred for 30 minutes. Saturated saline water was added to the reaction liquid, extracted with chloroform, and the organic layer was dried. The solvent was evaporated away under reduced pressure to obtain 2.54 g of methyl 2-(acetyloxy)-4-[(methylsulfonyl)oxy]butanoate as a brown liquid.

Workup

  1. extractionextracted with chloroform
  2. customthe organic layer was dried
  3. customThe solvent was evaporated away under reduced pressure

Sources & evidence

ORD record
ord-914501e3eeeb4df6b6a599ffa599d9cc
Source dataset
uspto-grants-2011_04
Patent number
US07932394B2

Reaction notes

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