HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl bromopyruvate → HCID 83966596, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl bromopyruvate | HCID 66144 | — |
| Reactant | 6-Aminopyridine-3-carbaldehyde | HCID 18404634 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 83966596 | HCID 83966596 | — |
Reaction Steps
An ethanol solution (8.0 ml) containing the compound (318 mg) obtained in Example 30-1 was added with 3-bromo-2-oxo-propionic acid ethyl ester (0.33 ml) and the whole was stirred at room temperature for 18 hours. The solvent was distilled off. The residue was purified through silica gel column chromatography (chloroform/methanol), thereby obtaining the subject compound (230 mg) as a yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07932281B2 |
| Source dataset | uspto-grants-2011_04 |
| ORD ID | ord-998e8314bff24073a553e1f6d7dfe2ea |
| Source note | uspto-grants-2011_04 |