反应详情

The compound (198.3 mg) obtained in Example 23-4 was dissolved in anhydrous dichloromethane (4.0 ml) and added with triethylamine (0.142 ml) and methanesulfonyl chloride (0.060 ml), and the whole was stirred at room temperature for 1 hour. After completion of the reaction, the resultant was washed with water and dried with anhydrous magnesium sulfate. The solvent was distilled off. The residue was purified through silica gel column chromatography (chloroform/ethyl acetate), thereby obtaining the subject compound (192.0 mg) as a colorless oily substance.

1. customAfter completion of the reaction
2. washthe resultant was washed with water
3. dry with materialdried with anhydrous magnesium sulfate
4. distillationThe solvent was distilled off
5. customThe residue was purified through silica gel column chromatography (chloroform/ethyl acetate)