Hydrochloric Acid → HCID 23155566, compound

Participants

Reaction Steps

The compound (234 mg) obtained in Example 88-2 was dissolved in methanol (2.5 ml) and added with 1 mol/l sodium hydroxide aqueous solution (2.5 ml) and the whole was stirred at room temperature for 16 hours. After completion of the reaction, the solution was neutralized with a 1 mol/l hydrochloric acid and the solvent was distilled off under reduced pressure. The residue was suspended in ethanol and then a white precipitate was filtrated out. The organic layer was distilled off under reduced pressure and the residue was dried under vacuum, thereby obtaining the subject compound (204 mg) as a pale-yellow oily substance.

Provenance & Evidence